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Pragmatic trials are trials designed to inform the practice of clinical trials in real life. They are often focused on the practical aspects of study design, such as the recruitment process and consent as well as adherence to the use of routinely available equipment.
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Pragmatic is a software company that provides a variety of casino games available on online gambling platforms. Pragmatic's iGaming solutions are used by the top operators and casinos that are located in the land. The company offers front-end site design tools, analysis tools and marketing, promotions, security, payment systems, customer support and bug reporting. The company also offers a safe environment with high-quality graphics, gameplay and security.
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RTP
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A pragmatic trial that uses a variety investigators and includes participants from diverse geographical locations is the Home Blood Pressure Management study (HBPM). This type of heterogeneity, that is crucial for a pragmatic trial to be reliable and lessen the chance of bias is also essential. A high degree of heterogeneity, however, can cause problems with the trial design.
Pragmatic Play is one of the major players in the live casino market, offers a variety of classic table games such as Blackjack and Roulette. The live studios of the company in Romania and Malta offer customers an authentic gaming experience and a wide selection of virtual betting options. The company also offers a variety of game shows that make online gambling more exciting and interactive. Some of these shows feature live hosts, whereas others are hosted by celebrities from the industry.
Mobile compatibility
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Legality
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Pragmatic trials seek to replicate real-life situations and attain maximum external validity. They are usually commissioned by policy makers and practitioners to inform their decision making. They also provide a useful way to identify the cause-effect relationship between an intervention and its outcomes. However, they should not be used to replace explanatory studies.
The concept of pragmatism is controversial, and there are questions about whether pragmatic trials should replace or complement them. Schwartz and Lellouch1 suggested the distinction between explanation trials, which prove a physiological or clinical hypothesis as well as pragmatic trials, which guide the policy and practice of. They also suggested a framework known as PRECIS for pragmatic trials.2 This tool attempted to define the traits of a practical study, including recruitment, design, implementation of the intervention, and follow-up.

There is an encouraging trend in the number of pragmatic trials published. A recent Medline query using the keywords pragmatic and naturalistic, limited to randomised controlled trials (RCTs) returned 34 articles. They are displayed in red on Figure 2. This is a sign that the health science community is becoming more acquaint to the subject of pragmatism. It is important to keep in mind that the majority of these trials were conducted in primary care settings.